I recently installed CachyOS with the default configuration. Following that, I installed my daily-use apps, Steam, and Lutris.
I thought I would give it a shot and try installing QSPICE. Unexpectedly, it ran with no issues at all. I ran the pre-installed demos and compared the results with QSPICE on Windows 10. There were no issues, except for some minor plotting artifacts.
I recently started using QSPICE on CachyOS. Except for a few visual artifacts in the plot windows, everything works fine—though plotting curves sometimes takes longer than it does on Windows 10.